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We further examined the protein expression and activation states of Smad2 and Smad3, which are downstream effectors of TGF signaling, in NP cells treated with L929 conditioned media

doi: 10.3389/fphar.2026.1796921 Received 28 January 2026 Revised 23 April 2026 Accepted 27 April 2026 Published 14 May 2026 Volume 17 - 2026 Edited by Arindam Kuila, Banasthali University, India Reviewed by Haiyun Xu, Wenzhou Medical University, China Lei Li, Second Military Medical University, China Updates Copyright 2026 Gao, Luo, Chen, Mi, He, Shang, Sui and Zheng

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Sublingual administration has been explored for some peptides, though sermorelin's molecular characteristics make this route less than ideal